The local party leader gets hospitalized, Dr. Gayathri tries her best to cure him, but he dies. The leader’s son is forced to take over while Dr. Gayathri tells him about the conspiracy over his father’s death.
Vezham begins with a series of murders in the Nilgiri Hills. The killing pattern points towards a serial killer on the loose. From there, we randomly move to a romantic song featuring the lead pair, Ashok (Ashok Selvan) and Leena (Iswarya Menon), who share lovely moments in the misty hills. On their way back through the woods, they are attacked… Five years after this horrific incident, Ashok is still reeling in trauma of being the only survivor of the attack. His only purpose in life is to find the killer. But all he remembers is the voice that says, ‘gammunu irundha uyiroda iruppa’.
Maaran (Sathyaraj) is a clerk in the district collector’s office. His life centres around his loving wife (Seetha), his son (Raghuvannan), and his daughter (Preethi Varma). Soft-spoken, and a Gandhian to the hilt, Maaran does not stand by any smear on the Mahatma’s name. Being a staunch patriot, he had even named his son Sudhandhiram.
Vetri and Maya love each other. Vetri’s twin brother Shakthi wants to molest Maya, so he is thrown by his parents. A few years later, villains kill Vetri, his parents, and Maya. They return as ghosts and eliminate them one by one. Shakthi returns as a powerful tantrik and kills all the villains for his family’s dispute. He now uses his power to kill Vetri, and at the same time, wants to have sex with Maya as revenge. In the end, good wins over evil.
The story begins with Kunjidhapadam (Aravindan) who comes from a small place to the city for an interview and he manages to find place to stay with his distant relative Subramanyam who is actually a defaulter on loans taken on interest. He is absconding but then leaves his key at a secret place. Kunjidhapadam takes the key and stays and he also manages to get a job. On the other hand, there is Angel (Charmy Kaur) who grows as an orphan and works with a mineral water company. She doesn’t have a place to stay so she locates those houses without occupants and stays there for a night and gets going in the morning. One such instance gets her to Kunjidhapadam’s house. All this apart, there are two dons Pavadai (Kota Srinivasa Rao) and Vembuli (Jayaprakash) who are out to kill each other and Vembuli is successful in killing Pavadai’s son. So he vows to kill Vembuli’s son by the 12th day ceremony of his son. A twist of fate occurs and Pavadai’s goons mistake Kunjidhapadam to be Subrahmanyam and get him to take money. Kunjidhapadam gives an idea to kill Vembuli’s son and he is given a 16-day deadline to kill else Pavadai threatens to kill him