Eeswaran tells the story of Periyasamy whose simple and joyous life turns into a nightmare with internal familial disputes.

Saravanan, a psychiatrist, meets up with his foster brother Senthilnathan alias Senthil, and his wife Ganga while on vacation. Senthil’s mother Kasthuri wanted Senthil to marry Priya, the daughter of his father’s cousin Kandaswamy, to reunite the two branches of the family after 30 years of separation because Senthil’s father chose to marry Kasthuri instead of Kandaswamy’s sister, Akhilandeshwari. Saravanan learns that Senthil had bought the Vettaiyapuram mansion, despite attempts by the local village elders to dissuade them, and moves in with them. Akhilandeshwari is jealous of Saravanan and plots to kill him with the help of her assistant Oomaiyan.
When the family visits their ancestral temple, the chief priest reveals the reason everyone fears the mansion. A hundred-and-fifty years ago, a king named Vettaiyan travelled to Vijayanagaram in Andhra Pradesh, where he met and fell in love with a dancer named Chandramukhi. However, she did not reciprocate his feelings as she was already in love with a dancer named Gunashekaran. As a result, Vettaiyan took her back to his palace by force. Unknown to him, Chandramukhi made Gunashekaran stay in a house nearby and had meetings with him secretly. When Vettaiyan discovered this, he beheaded Gunashekaran on Durgashtami and burnt Chandramukhi alive. As a result, Chandramukhi’s ghost tried to take revenge on Vettaiyan, who with the help of various priests and sorcerers from all over the country, tames the ghost by locking it up in a room located in the palace’s south-west corner. Priya is in love with Vishwanathan, a dance professor who reciprocates her feelings. Their love is supported by Saravanan, who requests Kandaswamy to arrange their marriage.

Krishna (Jayam Ravi) is a happy-go-lucky youth who excels in every field but always does strange and dangerous things to obtain a certain “kick” – a thrill or excitement that he craves. One such activity is secretly double-crossing his childhood friend Dass (Sathyan) while helping him elope. At this point, he meets Nisha (Tamannaah), who is shocked at his recklessness and writes him off as crazy. Krishna sets his sights on Nisha and woos her in a very unorthodox way; he begs her not to fall in love with him. After a host of comical situations involving Krishna’s caring but easygoing parents (Prabhu and Suhasini), local thugs (John Vijay and Mayilsamy), and an ever-present comic relief Jackson (Vadivelu), Nisha accepts Krishna’s love. However, she sets a condition: Krishna must stay in a well-paying job (he had resigned from other jobs due to lack of “kick”), and only then will she agree to marry him. Krishna accepts but soon resigns again for the same reason and tries to hide it from Nisha. When Nisha finds out, she breaks up with him and leaves him for good.

Anonymous cyber pirates are threatening to release a highly anticipated film featuring a massively popular star. It’s up to the cop Rudra to find the lawbreakers and bring them to justice.

An ambitious Gunjan Saxena eyes becoming a pilot after being drawn by the idea of a life in a cockpit. Despite facing reservations, she fulfils her dream and serves the country in the Kargil War.

Palakattu Madhavan (Vivek) is a lazy, irresponsible man. Embarrassed his wife Lakshmi (Sonia Agarwal) earns more than him, he quits his job out of spite. He then adopts the old woman Pattu Maami (Sheela) as a surrogate mother because she offers to pay cash for the opportunity. The character “Palakkattu Madhavan” is also an acknowledgement of a character with the same name in the movie Antha Ezhu Naatkal starring Bhagyaraj and Ambika.

Prabhu an average suburban man for whom his family is everything. His life is turned upside down when his daughter Satya is possessed by the ghost of a little boy.

Guna is local thug who is serious about the gangster life. When love enters his life, Guna is not ready to give up on love so he decides to reform his ways and settle down in the family life.

A man recovers a deleted video of his fiancé in the bath, but there’s trouble after his phone is stolen. He becomes a prime suspect when she goes missing.

During the political realm of N. T. Rama Rao, Shankar Narayana is an independent MLA of the constituency of Shankar Nagar, which is named after him, in Hyderabad, and is regarded as a champion for the poor. When a truck collides with the car his brother Satyam and he are in, Shankar goes into a coma. Except his family, everyone else presumes that he is killed in the accident. His son Ajay is a police officer in Mumbai who fights against the mafia and is on a mission to apprehend Mafia don Nayak who is involved in illegal drug trade, extortion and arms trafficking.
When he heads to Turkey in an undercover operation, he meets Prashanthi, the daughter of Ajay’s senior police officer and soon falls in love with her. She initially rejects his advances which makes him give up. However, he is successful in the undercover operation and arrests Nayak’s brother Bunty. After returning to India, he again meets Prashanthi and, to his surprise, she reciprocates his feelings. In an attempt to arrest Nayak, Bunty and the police commissioner is killed and Shankar’s loyal follower Sivayya reveals to Ajay that Nayak, along with Shankar’s rival, Mallesh Goud, and Shankar’s other followers Meka Narsingh Rao and Ambarpet Ganesh, were behind Shankar’s accident, which makes Ajay plot to kill all of them.

Kaakki Sattai has Murali (Kamal Haasan), a young man who trains very hard to become a police officer. Uma (Ambika) is his neighbour and they fall in love with each other while Uma supports Murali to achieve his goal but he is rejected after the physical test due to not having influence or money.
Angered by the rejection, Murali turns into a local rowdy. He causes trouble in his district and comes to the attention of a notorious smuggler and murderer, Vicky (Sathyaraj) and his partner Anand (Rajeev). After initial conflict between the two, Vicky recruits rowdy Murali into his gang. Murali becomes his most trusted member. He grows intimate with a girl, Anita (Madhavi), who is looking for personal revenge against Anand.

Gopikrishnan (Mammootty) and Anwar Hussain (Arjun) are tough police officers. They analyze farmers’ struggle and related social violence to put forward an amicable solution to have lasting harmony. They are highly disturbed by the terrorists’ infiltrations. Nandini (Sneha), an aviator, is Gopikrishnan’s wife and they are sad that they don’t have a child. The rest of the story deals with how they counter act against the terrorists and save the land.