The film opens with the killing of a police officer by cocaine mafia lord Bhai (Hareesh Peradi) and his henchmen. Kokila (Nayanthara) struggles to find a job to take care of her parents (Saranya Ponvannan and R. S. Shivaji) and sister (Jacqueline Fernandez). She stumbles on the cocaine smuggling business of Mohan (Charles Vinoth). When her mother is diagnosed with lung cancer, Kokila is forced to work for Mohan. Her cunning earns her a name in the business. The new inspector Guru (Saravanan) is a no-nonsense cop and cracks down on drug dealers. Kokila is almost caught a couple of times but manages to evade the authorities. She convinces Mohan to kill two of his henchmen suspected of leaking information and then decides to quit the business. Mohan seemingly accepts but tries to rape her. She beats him up and tries to flee with her family but is caught by Bobi, who had recruited her initially. He demands that she deliver a one last consignment of 100 kilos to Alphonse (Rajendran). Kokila is forced to accept and enlists the help of her family. She delivers the load, but it is revealed that she switched most of it for salt. She then tricks Bobi to double-cross Bhai and then frames him for swindling Bhai. She has him killed and continues the shipment run. On the way, she is caught by the police, who were Alphonse’s men in disguise. She manages to avoid getting raped and kills off her captors. Guru tracks her down and arrests her. Kokila makes a deal with him to nab Bhai and bring the whole drug business down. The plan works out, Bhai is shot dead, and Kokila and her family escape punishment. In the end, the family starts a business of Kolam powder, calling it ‘Kokila Kolamavu’.

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